Stem cells can be stimulated with concentrated growth factors in platelet rich plasma (PRP). Platelets play a critical role in several aspects of the healing process. Activated platelets release adhesion molecules that support clot formation for hemostasis, causing bleeding to stop. Platelets also release a multitude of growth factors with different functions and induce migration of stem cells to the damaged tissue during the healing and renewing process.
Platelets protect the environment from infection during the healing process by releasing several antimicrobial peptides. Growth factors secreted from platelets orchestrate formation of new blood vessels, resolve inflammation and stimulate tissue regeneration.
Stem cells isolated from the bone marrow or adipose tissue suspended in platelet rich plasma are injected into injured areas that typically do not heal well on their own, such as tendons, cartilage and even joints along the back. Stem cells can even benefit non-union fractures. This regenerative therapy using the body’s own healing mechanisms have shown to be far more effective and safer than corticosteroids.
Studies have proven that PRP combined with mesenchymal stem cells have the potential to restore cartilage, an effect superior to hyaluronic acid or corticosteroid injections into the knee. So, before you go under the knife, consider letting your body heal and regenerate itself for a lifetime of physical activity!